Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.K58delFs

c.174delT

Surrounding Variants

1 paper

NM_005465.7

p.C59fs

c.175_176fs

1 paper

NM_005465.7

p.C59delFs

c.176delC

1 paper

NM_005465.7

p.K58fs

c.172_173fs

1 paper

NM_005465.7

p.Q60*

c.178C>T

1 paper

NM_005465.7

p.Q60E

c.178C>G

1 paper

NM_005465.7

p.Q60K

c.178C>A

1 paper

NM_005465.7

p.Q60H

c.180G>T

1 paper

NM_005465.7

p.Q60H

c.180G>C

1 paper

NM_005465.7

p.L61F

c.183A>C

1 paper

NM_005465.7

p.M62I

c.186G>T

1 paper

NM_005465.7

p.M62I

c.186G>C

1 paper

NM_005465.7

p.M62I

c.186G>A