Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_005465.7

p.N53K

c.159C>A

Surrounding Variants

5 papers

NM_005465.7

p.N53K

c.159C>G

6 papers

NM_005465.7

p.F54Y

c.161T>A

1 paper

NM_005465.7

p.N53Y

c.157A>T

1 paper

NM_005465.7

p.N52insFs

c.155_156ins5

1 paper

NM_005465.7

p.S55L

c.164C>T

1 paper

NM_005465.7

p.N52D

c.154A>G

1 paper

NM_005465.7

p.G37_L51del15

c.109_152del45

3 papers

NM_005465.7

p.L51R

c.152T>G

1 paper

NM_005465.7

p.G37_L51del0

c.110_151del42

2 papers

NM_005465.7

p.L51I

c.151C>A

1 paper

NM_005465.7

p.Y49F

c.146A>T

1 paper

NM_005465.7

p.P48S

c.142C>T