Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.D46E

c.138T>A

Surrounding Variants

1 paper

NM_005465.7

p.D46E

c.138T>G

1 paper

NM_005465.7

p.D46H

c.136G>C

1 paper

NM_005465.7

p.D46N

c.136G>A

1 paper

NM_005465.7

p.P48S

c.142C>T

1 paper

NM_005465.7

p.V45M

c.133G>A

1 paper

NM_005465.7

p.D44Y

c.130G>T

1 paper

NM_005465.7

p.D44N

c.130G>A

1 paper

NM_005465.7

p.Y49F

c.146A>T

2 papers

NM_005465.7

p.Q43*

c.127C>T

2 papers

NM_005465.7

p.Q43E

c.127C>G

1 paper

NM_005465.7

p.Q43K

c.127C>A

2 papers

NM_005465.7

p.L51I

c.151C>A