Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_005465.7

p.D32E

c.96T>A

Surrounding Variants

3 papers

NM_005465.7

p.D32E

c.96T>G

1 paper

NM_005465.7

p.D32N

c.94G>A

1 paper

NM_005465.7

p.T31T

c.93A>G

1 paper

NM_005465.7

p.S34A

c.100T>G

2 papers

NM_005465.7

p.S34L

c.101C>T

1 paper

NM_005465.7

p.F35L

c.103T>C

1 paper

NM_005465.7

p.F35Y

c.104T>A

1 paper

NM_005465.7

p.F35L

c.105C>G

1 paper

NM_005465.7

p.F35L

c.105C>A

1 paper

NM_005465.7

p.L29*

c.86T>A

1 paper

NM_005465.7

p.L28delFs

c.82delG

2 papers

NM_005465.7

p.G37*

c.109G>T