aldehyde dehydrogenase 1 family member L2

FLJ38508

mtFDH

aldehyde dehydrogenase 1 family, member L2

mitochondrial 10-formyltetrahydrofolate dehydrogenase

Mitochondrial 10-formyltetrahydrofolate dehydrogenase

Aldehyde dehydrogenase family 1 member L2

Mitochondrial 10-FTHFDH

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010].

Varaico: Literature-Extracted Genetic Variants

ALDH1L2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols