Varaico: Literature-Extracted Genetic Variants

Gene:ALOX12
Variant:p.F62L

ALOX12

98 papers

RefSeq Summary

This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoid...

Pfam Domains

PLATaa 4–109UCSCPLAT/LH2 domain
Lipoxygenaseaa 176–649UCSCLipoxygenase

Gene Aliases

HGNC Name

arachidonate 12-lipoxygenase, 12S type

HGNC Alias Symbol

12S-LOX

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000697.3
p.F62L
c.184T>C
Surrounding Variants
1 paper
NM_000697.3
p.F62L
c.186C>A
1 paper
NM_000697.3
p.F62L
c.186C>G
1 paper
NM_000697.3
p.V63V
c.189G>C
1 paper
NM_000697.3
p.E55D
c.165G>C
1 paper
NM_000697.3
p.E55D
c.165G>T
1 paper
NM_000697.3
p.R80C
c.238C>T
1 paper
NM_000697.3
p.G87R
c.259G>A
1 paper
NM_000697.3
p.G87R
c.259G>C
1 paper
NM_000697.3
p.P95L
c.284C>T
1 paper
NM_000697.3
p.R98G
c.292C>G
1 paper
NM_000697.3
p.P41P
c.123C>G
1 paper
NM_000697.3
p.R40W
c.118C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."