Varaico: Literature-Extracted Genetic Variants

AMD1

24 papers

RefSeq Summary

This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proli...

Pfam Domains

SAM_decarboxaa 1–257UCSCAdenosylmethionine decarboxylase

SAM_decarboxaa 4–326UCSCAdenosylmethionine decarboxylase

SAM_decarboxaa 38–206UCSCAdenosylmethionine decarboxylase

Gene Aliases

HGNC Name

adenosylmethionine decarboxylase 1

HGNC Alias Symbol

SAMDC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001634.6

p.N138K

c.414T>G

Surrounding Variants

1 paper

NM_001634.6

p.N138K

c.414T>A

1 paper

NM_001634.6

p.E135Q

c.403G>C

1 paper

NM_001634.6

p.E133Q

c.397G>C

1 paper

NM_001634.6

p.E132Q

c.394G>C

1 paper

NM_001634.6

p.H122Y

c.364C>T

1 paper

NM_001634.6

p.K115E

c.343A>G

1 paper

NM_001634.6

p.R114C

c.340C>T

1 paper

NM_001634.6

p.A98A

c.294T>A

1 paper

NM_001634.6

p.L94fs

c.280_281fs

1 paper

NM_001634.6

p.C82S

c.245G>C

1 paper

NM_001634.6

p.C82S

c.244T>A

1 paper

NM_001634.6

p.S73C

c.218C>G