Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

1–12 of 235 variants

4 papers

NM_013366.4

p.A3G

c.8C>G

3 papers

NM_013366.4

p.A313T

c.937G>A

3 papers

NM_013366.4

p.Q628*

c.1882C>T

3 papers

NM_013366.4

p.R706H

c.2117G>A

2 papers

NM_013366.4

p.R322C

c.964C>T

2 papers

NM_013366.4

p.V419M

c.1255G>A

2 papers

NM_013366.4

p.E543A

c.1628A>C

2 papers

NM_013366.4

p.M554V

c.1660A>G

2 papers

NM_013366.4

p.V698M

c.2092G>A

2 papers

NM_013366.4

p.R724W

c.2170C>T

2 papers

NM_013366.4

p.D734N

c.2200G>A

2 papers

NM_013366.4

p.D737N

c.2209G>A