Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013366.4

p.D723E

c.2169C>G

Surrounding Variants

1 paper

NM_013366.4

p.D723E

c.2169C>A

2 papers

NM_013366.4

p.R724W

c.2170C>T

1 paper

NM_013366.4

p.R724Q

c.2171G>A

1 paper

NM_013366.4

p.R720Q

c.2159G>A

1 paper

NM_013366.4

p.E719V

c.2156A>T

1 paper

NM_013366.4

p.V728A

c.2183T>C

2 papers

NM_013366.4

p.D734N

c.2200G>A

1 paper

NM_013366.4

p.E735D

c.2205G>T

1 paper

NM_013366.4

p.E735D

c.2205G>C

1 paper

NM_013366.4

p.G711fs

c.2131_2132fs

1 paper

NM_013366.4

p.P710delFs

c.2130delG

2 papers

NM_013366.4

p.D737N

c.2209G>A