Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013366.4

p.V611D

c.1832T>A

Surrounding Variants

1 paper

NM_013366.4

p.E627D

c.1881G>T

1 paper

NM_013366.4

p.E627D

c.1881G>C

3 papers

NM_013366.4

p.Q628*

c.1882C>T

1 paper

NM_013366.4

p.A593V

c.1778C>T

1 paper

NM_013366.4

p.G590V

c.1769G>T

1 paper

NM_013366.4

p.E584V

c.1751A>T

1 paper

NM_013366.4

p.E579D

c.1737G>T

1 paper

NM_013366.4

p.E579D

c.1737G>C

1 paper

NM_013366.4

p.E579G

c.1736A>G

1 paper

NM_013366.4

p.R575Q

c.1724G>A

1 paper

NM_013366.4

p.R568H

c.1703G>A

1 paper

NM_013366.4

p.S567C

c.1700C>G