Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_013366.4

p.M554V

c.1660A>G

Surrounding Variants

1 paper

NM_013366.4

p.F556L

c.1666T>C

1 paper

NM_013366.4

p.F556L

c.1668C>G

1 paper

NM_013366.4

p.F556L

c.1668C>A

1 paper

NM_013366.4

p.R548H

c.1643G>A

1 paper

NM_013366.4

p.R548C

c.1642C>T

1 paper

NM_013366.4

p.M560I

c.1680G>T

1 paper

NM_013366.4

p.M560I

c.1680G>C

1 paper

NM_013366.4

p.M560I

c.1680G>A

1 paper

NM_013366.4

p.L545L

c.1633C>T

2 papers

NM_013366.4

p.E543A

c.1628A>C

1 paper

NM_013366.4

p.V542A

c.1625T>C

1 paper

NM_013366.4

p.R540C

c.1618C>T