Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_013366.4

p.V419M

c.1255G>A

Surrounding Variants

1 paper

NM_013366.4

p.S413P

c.1237T>C

1 paper

NM_013366.4

p.P412H

c.1235C>A

1 paper

NM_013366.4

p.R426C

c.1276C>T

1 paper

NM_013366.4

p.L428V

c.1282C>G

1 paper

NM_013366.4

p.V409M

c.1225G>A

1 paper

NM_013366.4

p.A406S

c.1216G>T

1 paper

NM_013366.4

p.A403D

c.1208C>A

1 paper

NM_013366.4

p.I396insFs

c.1187_1188insGG

1 paper

NM_013366.4

p.V391I

c.1171G>A

1 paper

NM_013366.4

p.P389P

c.1167A>G

1 paper

NM_013366.4

p.L378F

c.1132C>T

1 paper

NM_013366.4

p.S377F

c.1130C>T