Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013366.4

p.P312R

c.935C>G

Surrounding Variants

3 papers

NM_013366.4

p.A313T

c.937G>A

1 paper

NM_013366.4

p.P315T

c.943C>A

1 paper

NM_013366.4

p.E316K

c.946G>A

1 paper

NM_013366.4

p.G308fs

c.922_923fs

1 paper

NM_013366.4

p.T320N

c.959C>A

1 paper

NM_013366.4

p.V303G

c.908T>G

2 papers

NM_013366.4

p.R322C

c.964C>T

1 paper

NM_013366.4

p.R322H

c.965G>A

1 paper

NM_013366.4

p.K302R

c.905A>G

1 paper

NM_013366.4

p.R323C

c.967C>T

1 paper

NM_013366.4

p.G298S

c.892G>A

1 paper

NM_013366.4

p.V328M

c.982G>A