Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013366.4

p.P219T

c.655C>A

Surrounding Variants

1 paper

NM_013366.4

p.Q217E

c.649C>G

1 paper

NM_013366.4

p.L215F

c.643C>T

1 paper

NM_013366.4

p.G223E

c.668G>A

1 paper

NM_013366.4

p.Y213C

c.638A>G

1 paper

NM_013366.4

p.R210C

c.628C>T

1 paper

NM_013366.4

p.Y207N

c.619T>A

1 paper

NM_013366.4

p.W232R

c.694T>C

1 paper

NM_013366.4

p.W232R

c.694T>A

1 paper

NM_013366.4

p.E202K

c.604G>A

1 paper

NM_013366.4

p.G201R

c.601G>A

1 paper

NM_013366.4

p.P197S

c.589C>T

1 paper

NM_013366.4

p.G194S

c.580G>A