Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013366.4

p.L129Q

c.386T>A

Surrounding Variants

1 paper

NM_013366.4

p.L131Q

c.392T>A

1 paper

NM_013366.4

p.P124S

c.370C>T

1 paper

NM_013366.4

p.R137H

c.410G>A

1 paper

NM_013366.4

p.L138M

c.412C>A

1 paper

NM_013366.4

p.L140S

c.419T>C

1 paper

NM_013366.4

p.F115Y

c.344T>A

1 paper

NM_013366.4

p.G143G

c.429C>G

1 paper

NM_013366.4

p.T144A

c.430A>G

1 paper

NM_013366.4

p.T144I

c.431C>T

1 paper

NM_013366.4

p.A114S

c.340G>T

1 paper

NM_013366.4

p.A146_Q147delFs

c.438_439delGA

1 paper

NM_013366.4

p.L109F

c.327G>T