Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013366.4

p.G46S

c.136G>A

Surrounding Variants

1 paper

NM_013366.4

p.V48I

c.142G>A

1 paper

NM_013366.4

p.R43R

c.127C>A

1 paper

NM_013366.4

p.V40M

c.118G>A

1 paper

NM_013366.4

p.E54delFs

c.160delC

1 paper

NM_013366.4

p.E54fs

c.160_161fs

1 paper

NM_013366.4

p.V59M

c.175G>A

1 paper

NM_013366.4

p.E53_V59del0

c.159_176del18

1 paper

NM_013366.4

p.V61A

c.182T>C

1 paper

NM_013366.4

p.H65Y

c.193C>T

1 paper

NM_013366.4

p.G66W

c.196G>T

1 paper

NM_013366.4

p.V78E

c.233T>A

1 paper

NM_013366.4

p.D82G

c.245A>G