Varaico: Literature-Extracted Genetic Variants

ANAPC2

155 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

TPR_ANAPC2aa 321–431UCSCANAPC2-like, TPR repeats

Cullin_ABaa 595–726UCSCCullin alpha+beta domain

ANAPC2aa 757–817UCSCAnaphase promoting complex (APC) subunit 2

Gene Aliases

HGNC Name

anaphase promoting complex subunit 2

HGNC Alias Symbol

KIAA1406

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_013366.4

p.A3G

c.8C>G

Surrounding Variants

1 paper

NM_013366.4

p.A3insFs

c.7_8ins19

1 paper

NM_013366.4

p.A4T

c.10G>A

1 paper

NM_013366.4

p.V5L

c.13G>C

1 paper

NM_013366.4

p.M1I

c.3G>A

1 paper

NM_013366.4

p.V5A

c.14T>C

1 paper

NM_013366.4

p.G10R

c.28G>C

1 paper

NM_013366.4

p.G10R

c.28G>A

1 paper

NM_013366.4

p.V22M

c.64G>A

1 paper

NM_013366.4

p.V22_A23ins3

c.66_67ins9

1 paper

NM_013366.4

p.T26P

c.76A>C

1 paper

NM_013366.4

p.V40M

c.118G>A

1 paper

NM_013366.4

p.R43R

c.127C>A