Varaico: Literature-Extracted Genetic Variants

ANAPC4

85 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

ANAPC4_WD40aa 26–118UCSCAnaphase-promoting complex subunit 4 WD40 domain

ANAPC4aa 232–431UCSCAnaphase-promoting complex, cyclosome, subunit 4

WD40_APC4_C-halfaa 575–745UCSCAPC4, WD40 domain C-terminal half

Gene Aliases

HGNC Name

anaphase promoting complex subunit 4

HGNC Alias Symbol

APC4

Papers

RefSeq ID

Protein change

DNA change

1–12 of 72 variants

5 papers

NM_013367.3

p.R465Q

c.1394G>A

3 papers

NM_013367.3

p.S777S

c.2331G>T

2 papers

NM_013367.3

p.I155V

c.463A>G

2 papers

NM_013367.3

p.I195T

c.584T>C

2 papers

NM_013367.3

p.C271R

c.811T>C

2 papers

NM_013367.3

p.F707F

c.2121T>C

2 papers

NM_013367.3

p.K772R

c.2315A>G

2 papers

NM_013367.3

p.K798R

c.2393A>G

1 paper

NM_013367.3

p.S10F

c.29C>T

1 paper

NM_013367.3

p.E16K

c.46G>A

1 paper

NM_013367.3

p.K17M

c.50A>T

1 paper

NM_013367.3

p.K31N

c.93G>C