Varaico: Literature-Extracted Genetic Variants

ANAPC4

85 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

ANAPC4_WD40aa 26–118UCSCAnaphase-promoting complex subunit 4 WD40 domain

ANAPC4aa 232–431UCSCAnaphase-promoting complex, cyclosome, subunit 4

WD40_APC4_C-halfaa 575–745UCSCAPC4, WD40 domain C-terminal half

Gene Aliases

HGNC Name

anaphase promoting complex subunit 4

HGNC Alias Symbol

APC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013367.3

p.K17M

c.50A>T

Surrounding Variants

1 paper

NM_013367.3

p.E16K

c.46G>A

1 paper

NM_013367.3

p.S10F

c.29C>T

1 paper

NM_013367.3

p.K31N

c.93G>C

1 paper

NM_013367.3

p.K31N

c.93G>T

1 paper

NM_013367.3

p.T40I

c.119C>T

1 paper

NM_013367.3

p.L45V

c.133T>G

1 paper

NM_013367.3

p.L45*

c.134T>A

1 paper

NM_013367.3

p.L45*

c.134T>G

1 paper

NM_013367.3

p.R48Q

c.143G>A

1 paper

NM_013367.3

p.A50T

c.148G>A

1 paper

NM_013367.3

p.P59S

c.175C>T

1 paper

NM_013367.3

p.P59P

c.177A>G