Varaico: Literature-Extracted Genetic Variants

ANAPC4

85 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

ANAPC4_WD40aa 26–118UCSCAnaphase-promoting complex subunit 4 WD40 domain

ANAPC4aa 232–431UCSCAnaphase-promoting complex, cyclosome, subunit 4

WD40_APC4_C-halfaa 575–745UCSCAPC4, WD40 domain C-terminal half

Gene Aliases

HGNC Name

anaphase promoting complex subunit 4

HGNC Alias Symbol

APC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_013367.3

p.I195T

c.584T>C

Surrounding Variants

1 paper

NM_013367.3

p.Y190Y

c.570T>C

1 paper

NM_013367.3

p.I201V

c.601A>G

1 paper

NM_013367.3

p.L214insFs

c.641_642insC

1 paper

NM_013367.3

p.V220L

c.658G>C

1 paper

NM_013367.3

p.R172K

c.515G>A

1 paper

NM_013367.3

p.I155insFs

c.464dupT

2 papers

NM_013367.3

p.I155V

c.463A>G

1 paper

NM_013367.3

p.T152N

c.455C>A

1 paper

NM_013367.3

p.F244Y

c.731T>A

1 paper

NM_013367.3

p.F244C

c.731T>G

1 paper

NM_013367.3

p.L267ins5

c.799_800ins15

2 papers

NM_013367.3

p.C271R

c.811T>C