Varaico: Literature-Extracted Genetic Variants

ANAPC4

85 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

ANAPC4_WD40aa 26–118UCSCAnaphase-promoting complex subunit 4 WD40 domain

ANAPC4aa 232–431UCSCAnaphase-promoting complex, cyclosome, subunit 4

WD40_APC4_C-halfaa 575–745UCSCAPC4, WD40 domain C-terminal half

Gene Aliases

HGNC Name

anaphase promoting complex subunit 4

HGNC Alias Symbol

APC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_013367.3

p.R465Q

c.1394G>A

Surrounding Variants

1 paper

NM_013367.3

p.G467R

c.1399G>A

1 paper

NM_013367.3

p.Y498H

c.1492T>C

1 paper

NM_013367.3

p.Q502H

c.1506A>C

1 paper

NM_013367.3

p.Q502H

c.1506A>T

1 paper

NM_013367.3

p.N503H

c.1507A>C

1 paper

NM_013367.3

p.S504R

c.1510A>C

1 paper

NM_013367.3

p.F417C

c.1250T>G

1 paper

NM_013367.3

p.Q535R

c.1604A>G

1 paper

NM_013367.3

p.S547P

c.1639T>C

1 paper

NM_013367.3

p.L575Splc

c.1724+1G>C

1 paper

NM_013367.3

p.I616I

c.1848T>A

1 paper

NM_013367.3

p.A617S

c.1849G>T