Varaico: Literature-Extracted Genetic Variants

ANAPC4

85 papers

RefSeq Summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and ana...

Pfam Domains

ANAPC4_WD40aa 26–118UCSCAnaphase-promoting complex subunit 4 WD40 domain

ANAPC4aa 232–431UCSCAnaphase-promoting complex, cyclosome, subunit 4

WD40_APC4_C-halfaa 575–745UCSCAPC4, WD40 domain C-terminal half

Gene Aliases

HGNC Name

anaphase promoting complex subunit 4

HGNC Alias Symbol

APC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013367.3

p.A617S

c.1849G>T

Surrounding Variants

1 paper

NM_013367.3

p.I616I

c.1848T>A

1 paper

NM_013367.3

p.A641S

c.1921G>T

1 paper

NM_013367.3

p.T648T

c.1944T>C

1 paper

NM_013367.3

p.L575Splc

c.1724+1G>C

1 paper

NM_013367.3

p.R659C

c.1975C>T

1 paper

NM_013367.3

p.R659H

c.1976G>A

1 paper

NM_013367.3

p.S547P

c.1639T>C

1 paper

NM_013367.3

p.Q535R

c.1604A>G

1 paper

NM_013367.3

p.I700V

c.2098A>G

2 papers

NM_013367.3

p.F707F

c.2121T>C

1 paper

NM_013367.3

p.H710R

c.2129A>G

1 paper

NM_013367.3

p.W711*

c.2132G>A