Varaico: Literature-Extracted Genetic Variants

ANAPC5

74 papers

RefSeq Summary

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a n...

Pfam Domains

Apc5_Naa 23–169UCSCAnaphase-promoting complex subunit 5, N-terminal domain

ANAPC5aa 254–354UCSCAnaphase-promoting complex subunit 5

ANAPC5aa 400–495UCSCAnaphase-promoting complex subunit 5

Gene Aliases

HGNC Name

anaphase promoting complex subunit 5

HGNC Alias Symbol

APC5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_016237.5

p.N521S

c.1562A>G

Surrounding Variants

1 paper

NM_016237.5

p.C510R

c.1528T>C

1 paper

NM_016237.5

p.H503D

c.1507C>G

1 paper

NM_016237.5

p.L493S

c.1478T>C

1 paper

NM_016237.5

p.L493M

c.1477T>A

1 paper

NM_016237.5

p.H492H

c.1476C>T

1 paper

NM_016237.5

p.G481V

c.1442G>T

2 papers

NM_016237.5

p.A548V

c.1643C>T

1 paper

NM_016237.5

p.M557I

c.1671G>A

1 paper

NM_016237.5

p.E559*

c.1675G>T

1 paper

NM_016237.5

p.K575E

c.1723A>G

1 paper

NM_016237.5

p.A588P

c.1762G>C

1 paper

NM_016237.5

p.A600V

c.1799C>T