Varaico: Literature-Extracted Genetic Variants

Gene:ANGPT2
Variant:p.K411K

ANGPT2

104 papers

RefSeq Summary

This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endo...

Pfam Domains

ANG-1aa 159–264UCSCANG-1-like domain
Fibrinogen_Caa 280–494UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

angiopoietin 2

HGNC Alias Symbol

Ang2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001118887.2
p.K411K
c.1233A>G
Surrounding Variants
1 paper
NM_001118887.2
p.A409V
c.1226C>T
1 paper
NM_001147.3
p.S415N
c.1244G>A
1 paper
NM_001147.3
p.N430S
c.1289A>G
1 paper
NM_001118887.2
p.N429T
c.1286A>C
1 paper
NM_001147.3
p.D431N
c.1291G>A
2 papers
NM_001147.3
p.I434V
c.1300A>G
NM_001118887.2
p.I433V
c.1297A>G
1 paper
NM_001147.3
p.C435S
c.1303T>A
1 paper
NM_001147.3
p.C435S
c.1304G>C
1 paper
NM_001147.3
p.M440L
c.1318A>T
1 paper
NM_001147.3
p.M440L
c.1318A>C
1 paper
NM_001147.3
p.T442I
c.1325C>T
1 paper
NM_001118887.2
p.S392insFs
c.1175_1176insA
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."