adaptor related protein complex 2 subunit alpha 1

CLAPA1

ADTAA

adaptor related protein complex 2 alpha 1 subunit

AP-2 complex subunit alpha-1

100 kDa coated vesicle protein A

Adaptor protein complex AP-2 subunit alpha-1

Adaptor-related protein complex 2 subunit alpha-1

Alpha-adaptin A

Alpha1-adaptin

Clathrin assembly protein complex 2 alpha-A large chain

Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit

This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

AP2A1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbols