Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.E84K

APOE

2,396 papers

RefSeq Summary

The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich li...

Pfam Domains

Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain
Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain

Gene Aliases

HGNC Name

apolipoprotein E

HGNC Previous Symbol

AD2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000041.4
p.E84K
c.250G>A
Surrounding Variants
1 paper
NM_000041.4
p.E84*
c.250G>T
2 papers
NM_000041.4
p.E84V
c.251A>T
2 papers
NM_000041.4
p.D83D
c.249C>T
1 paper
NM_000041.4
p.T85fs
c.253_254fs
1 paper
NM_000041.4
p.T85I
c.254C>T
4 papers
NM_000041.4
p.M82I
c.246G>A
3 papers
NM_000041.4
p.M82I
c.246G>C
3 papers
NM_000041.4
p.M82I
c.246G>T
1 paper
NM_000041.4
p.T85T
c.255C>A
1 paper
NM_000041.4
p.M82T
c.245T>C
1 paper
NM_000041.4
p.M82R
c.245T>G
1 paper
NM_000041.4
p.M86L
c.256A>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."