Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.L89insFs

APOE

2,396 papers

RefSeq Summary

The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich li...

Pfam Domains

Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain
Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain

Gene Aliases

HGNC Name

apolipoprotein E

HGNC Previous Symbol

AD2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000041.4
p.L89insFs
c.265_266insT
Surrounding Variants
1 paper
NM_000041.4
p.E88V
c.263A>T
2 papers
NM_000041.4
p.E88Q
c.262G>C
2 papers
NM_000041.4
p.L89S
c.266T>C
1 paper
NM_000041.4
p.K87N
c.261G>C
1 paper
NM_000041.4
p.K87N
c.261G>T
1 paper
NM_000041.4
p.K90_A91ins4
c.268_272ins12
1 paper
NM_000041.4
p.K90E
c.268A>G
1 paper
NM_000041.4
p.K90delFs
c.270delG
1 paper
NM_000041.4
p.A91P
c.271G>C
1 paper
NM_000041.4
p.M86L
c.256A>C
1 paper
NM_000041.4
p.M86V
c.256A>G
1 paper
NM_000041.4
p.T85T
c.255C>A
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