Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.E263K

APOE

2,396 papers

RefSeq Summary

The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich li...

Pfam Domains

Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain
Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain

Gene Aliases

HGNC Name

apolipoprotein E

HGNC Previous Symbol

AD2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
17 papers
NM_000041.4
p.E263K
c.787G>A
Surrounding Variants
1 paper
NM_000041.4
p.E262D
c.786G>C
1 paper
NM_000041.4
p.E262insFs
c.785_786insG
2 papers
NM_000041.4
p.E262G
c.785A>G
18 papers
NM_000041.4
p.E262K
c.784G>A
1 paper
NM_000041.4
p.L261P
c.782T>C
1 paper
NM_000041.4
p.L261R
c.782T>G
2 papers
NM_000041.4
p.A259P
c.775G>C
2 papers
NM_000041.4
p.R258H
c.773G>A
1 paper
NM_000041.4
p.Q267Q
c.801G>A
1 paper
NM_000041.4
p.I268V
c.802A>G
1 paper
NM_000041.4
p.I268M
c.804A>G
24 papers
NM_000041.4
p.R269G
c.805C>G
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