Varaico: Literature-Extracted Genetic Variants

ARAP3

135 papers

RefSeq Summary

This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangement...

Pfam Domains

SAM_2aa 4–64UCSCSAM domain (Sterile alpha motif)

PHaa 288–379UCSCPH domain

ArfGapaa 489–607UCSCPutative GTPase activating protein for Arf

RhoGAPaa 920–1068UCSCRhoGAP domain

RAaa 1117–1209UCSCRas association (RalGDS/AF-6) domain

PHaa 1227–1325UCSCPH domain

Gene Aliases

HGNC Name

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

HGNC Previous Symbol

CENTD3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 185 variants

6 papers

NM_022481.6

p.T1428P

c.4282A>C

3 papers

NM_022481.6

p.D513N

c.1537G>A

3 papers

NM_022481.6

p.A1201A

c.3603T>C

3 papers

NM_022481.6

p.E1261K

c.3781G>A

3 papers

NM_022481.6

p.R1478Q

c.4433G>A

2 papers

NM_022481.6

p.S280F

c.839C>T

2 papers

NM_022481.6

p.M318I

c.954G>T

2 papers

NM_022481.6

p.M318I

c.954G>C

2 papers

NM_022481.6

p.M318I

c.954G>A

2 papers

NM_022481.6

p.R388P

c.1163G>C

2 papers

NM_022481.6

p.R397H

c.1190G>A

2 papers

NM_022481.6

p.R471W

c.1411C>T