Varaico: Literature-Extracted Genetic Variants

ARAP3

135 papers

RefSeq Summary

This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangement...

Pfam Domains

SAM_2aa 4–64UCSCSAM domain (Sterile alpha motif)

PHaa 288–379UCSCPH domain

ArfGapaa 489–607UCSCPutative GTPase activating protein for Arf

RhoGAPaa 920–1068UCSCRhoGAP domain

RAaa 1117–1209UCSCRas association (RalGDS/AF-6) domain

PHaa 1227–1325UCSCPH domain

Gene Aliases

HGNC Name

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

HGNC Previous Symbol

CENTD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022481.6

p.L1321F

c.3961C>T

Surrounding Variants

1 paper

NM_022481.6

p.H1325Y

c.3973C>T

1 paper

NM_022481.6

p.R1335C

c.4003C>T

1 paper

NM_022481.6

p.G1356W

c.4066G>T

1 paper

NM_022481.6

p.G1356G

c.4068G>A

1 paper

NM_022481.6

p.A1361V

c.4082C>T

1 paper

NM_022481.6

p.R1269W

c.3805C>T

1 paper

NM_022481.6

p.R1376W

c.4126C>T

3 papers

NM_022481.6

p.E1261K

c.3781G>A

1 paper

NM_022481.6

p.L1258L

c.3774G>T

1 paper

NM_022481.6

p.R1254H

c.3761G>A

1 paper

NM_022481.6

p.R1233H

c.3698G>A

1 paper

NM_022481.6

p.R1231Q

c.3692G>A