Varaico: Literature-Extracted Genetic Variants

ARAP3

135 papers

RefSeq Summary

This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangement...

Pfam Domains

SAM_2aa 4–64UCSCSAM domain (Sterile alpha motif)

PHaa 288–379UCSCPH domain

ArfGapaa 489–607UCSCPutative GTPase activating protein for Arf

RhoGAPaa 920–1068UCSCRhoGAP domain

RAaa 1117–1209UCSCRas association (RalGDS/AF-6) domain

PHaa 1227–1325UCSCPH domain

Gene Aliases

HGNC Name

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

HGNC Previous Symbol

CENTD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022481.6

p.R388delFs

c.1162delG

Surrounding Variants

1 paper

NM_022481.6

p.R388insFs

c.1162dupC

2 papers

NM_022481.6

p.R388P

c.1163G>C

1 paper

NM_022481.6

p.R388ins11

c.1162_1163ins33

1 paper

NM_022481.6

p.R388fs

c.1162_1163fs

1 paper

NM_022481.6

p.P395L

c.1184C>T

2 papers

NM_022481.6

p.R397H

c.1190G>A

1 paper

NM_022481.6

p.T398M

c.1193C>T

1 paper

NM_022481.6

p.G399D

c.1196G>A

1 paper

NM_022481.6

p.M400I

c.1200G>T

1 paper

NM_022481.6

p.M400I

c.1200G>C

1 paper

NM_022481.6

p.M400I

c.1200G>A

1 paper

NM_022481.6

p.T373R

c.1118C>G