Varaico: Literature-Extracted Genetic Variants

ARAP3

135 papers

RefSeq Summary

This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangement...

Pfam Domains

SAM_2aa 4–64UCSCSAM domain (Sterile alpha motif)

PHaa 288–379UCSCPH domain

ArfGapaa 489–607UCSCPutative GTPase activating protein for Arf

RhoGAPaa 920–1068UCSCRhoGAP domain

RAaa 1117–1209UCSCRas association (RalGDS/AF-6) domain

PHaa 1227–1325UCSCPH domain

Gene Aliases

HGNC Name

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

HGNC Previous Symbol

CENTD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022481.6

p.F357L

c.1071C>A

Surrounding Variants

1 paper

NM_022481.6

p.F357L

c.1071C>G

1 paper

NM_022481.6

p.V358M

c.1072G>A

1 paper

NM_022481.6

p.F357L

c.1069T>C

1 paper

NM_022481.6

p.K347N

c.1041G>T

1 paper

NM_022481.6

p.K347N

c.1041G>C

1 paper

NM_022481.6

p.I337V

c.1009A>G

1 paper

NM_022481.6

p.P333S

c.997C>T

1 paper

NM_022481.6

p.W370*

c.1109G>A

1 paper

NM_022481.6

p.W370*

c.1110G>A

1 paper

NM_022481.6

p.T373R

c.1118C>G

1 paper

NM_022481.6

p.R388fs

c.1162_1163fs

1 paper

NM_022481.6

p.R388insFs

c.1162dupC