Varaico: Literature-Extracted Genetic Variants

ARAP3

135 papers

RefSeq Summary

This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangement...

Pfam Domains

SAM_2aa 4–64UCSCSAM domain (Sterile alpha motif)

PHaa 288–379UCSCPH domain

ArfGapaa 489–607UCSCPutative GTPase activating protein for Arf

RhoGAPaa 920–1068UCSCRhoGAP domain

RAaa 1117–1209UCSCRas association (RalGDS/AF-6) domain

PHaa 1227–1325UCSCPH domain

Gene Aliases

HGNC Name

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

HGNC Previous Symbol

CENTD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_022481.6

p.S280F

c.839C>T

Surrounding Variants

1 paper

NM_022481.6

p.S274L

c.821C>T

1 paper

NM_022481.6

p.T287T

c.861G>T

1 paper

NM_022481.6

p.D271Y

c.811G>T

1 paper

NM_022481.6

p.S269N

c.806G>A

1 paper

NM_022481.6

p.D295N

c.883G>A

1 paper

NM_022481.6

p.G301Splc

c.902+4G>C

1 paper

NM_022481.6

p.G254*

c.760G>T

1 paper

NM_022481.6

p.G301G

c.903A>C

1 paper

NM_022481.6

p.R308H

c.923G>A

2 papers

NM_022481.6

p.M318I

c.954G>T

2 papers

NM_022481.6

p.M318I

c.954G>C

2 papers

NM_022481.6

p.M318I

c.954G>A