Rho GTPase activating protein 22

RhoGAP2

Rho GTPase-activating protein 22

Rho-type GTPase-activating protein 22

This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

Varaico: Literature-Extracted Genetic Variants

ARHGAP22

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol