Varaico: Literature-Extracted Genetic Variants

Gene:ARHGAP26
Variant:p.*760fs

ARHGAP26

133 papers

RefSeq Summary

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins i...

Pfam Domains

BAR_3aa 6–249UCSCBAR domain of APPL family
PHaa 266–366UCSCPH domain
RhoGAPaa 391–541UCSCRhoGAP domain
SH3_9aa 763–812UCSCVariant SH3 domain

Gene Aliases

HGNC Name

Rho GTPase activating protein 26

HGNC Alias Symbols

GRAF; KIAA0621; OPHN1L; OPHN1L1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001135608.3
p.*760fs
c.2278_2279fs
Surrounding Variants
4 papers
NM_001135608.3
p.*760S
c.2279A>C
1 paper
NM_001135608.3
p.E741Q
c.2221G>C
2 papers
NM_001135608.3
p.N730N
c.2190C>T
2 papers
NM_001135608.3
p.D729N
c.2185G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."