Varaico: Literature-Extracted Genetic Variants

ARHGEF26

88 papers

RefSeq Summary

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifical...

Pfam Domains

RhoGEFaa 443–621UCSCRhoGEF domain

SOS1_NGEF_PHaa 650–779UCSCSOS1/NGEF-like PH domain

SH3_1aa 799–842UCSCSH3 domain

Gene Aliases

HGNC Name

Rho guanine nucleotide exchange factor 26

HGNC Alias Symbols

DKFZP434D146; SGEF

Papers

RefSeq ID

Protein change

DNA change

1–12 of 102 variants

6 papers

NM_015595.4

p.V29L

c.85G>C

4 papers

NM_015595.4

p.F203S

c.608T>C

3 papers

NM_015595.4

p.F9I

c.25T>A

3 papers

NM_015595.4

p.L60delins

c.178_179delinsTC

2 papers

NM_015595.4

p.L60F

c.178C>T

2 papers

NM_015595.4

p.L60P

c.179T>C

2 papers

NM_015595.4

p.N687K

c.2061C>G

1 paper

NM_015595.4

p.S5T

c.14G>C

1 paper

NM_015595.4

p.D8N

c.22G>A

1 paper

NM_015595.4

p.T15I

c.44C>T

1 paper

NM_015595.4

p.R19W

c.55C>T

1 paper

NM_015595.4

p.P26P

c.78C>A