Varaico: Literature-Extracted Genetic Variants

ARHGEF26

88 papers

RefSeq Summary

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifical...

Pfam Domains

RhoGEFaa 443–621UCSCRhoGEF domain

SOS1_NGEF_PHaa 650–779UCSCSOS1/NGEF-like PH domain

SH3_1aa 799–842UCSCSH3 domain

Gene Aliases

HGNC Name

Rho guanine nucleotide exchange factor 26

HGNC Alias Symbols

DKFZP434D146; SGEF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015595.4

p.L60P

c.179T>C

Surrounding Variants

2 papers

NM_015595.4

p.L60F

c.178C>T

3 papers

NM_015595.4

p.L60delins

c.178_179delinsTC

1 paper

NM_015595.4

p.D50A

c.149A>C

1 paper

NM_015595.4

p.L46delFs

c.137_138delTA

1 paper

NM_015595.4

p.G45R

c.133G>A

1 paper

NM_015595.4

p.G45R

c.133G>C

1 paper

NM_015595.4

p.T76M

c.227C>T

1 paper

NM_015595.4

p.N44_I48delFs

c.132_142del11

1 paper

NM_015595.4

p.S80R

c.238A>C

1 paper

NM_015595.4

p.S80R

c.240C>A

1 paper

NM_015595.4

p.S80R

c.240C>G

1 paper

NM_015595.4

p.P81R

c.242C>G