Varaico: Literature-Extracted Genetic Variants

ARHGEF26

88 papers

RefSeq Summary

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifical...

Pfam Domains

RhoGEFaa 443–621UCSCRhoGEF domain

SOS1_NGEF_PHaa 650–779UCSCSOS1/NGEF-like PH domain

SH3_1aa 799–842UCSCSH3 domain

Gene Aliases

HGNC Name

Rho guanine nucleotide exchange factor 26

HGNC Alias Symbols

DKFZP434D146; SGEF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015595.4

p.N93S

c.278A>G

Surrounding Variants

1 paper

NM_015595.4

p.A92D

c.275C>A

1 paper

NM_015595.4

p.R88insFs

c.262_263insA

1 paper

NM_015595.4

p.R88fs

c.262_263fs

1 paper

NM_015595.4

p.Q87insFs

c.259_260insAG

1 paper

NM_015595.4

p.Q87ins1

c.259_260insAGA

1 paper

NM_015595.4

p.L84P

c.251T>C

1 paper

NM_015595.4

p.L83F

c.247C>T

1 paper

NM_015595.4

p.P81R

c.242C>G

1 paper

NM_015595.4

p.S80R

c.240C>A

1 paper

NM_015595.4

p.S80R

c.240C>G

1 paper

NM_015595.4

p.S80R

c.238A>C

1 paper

NM_015595.4

p.R110W

c.328C>T