Varaico: Literature-Extracted Genetic Variants

ARHGEF26

88 papers

RefSeq Summary

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifical...

Pfam Domains

RhoGEFaa 443–621UCSCRhoGEF domain

SOS1_NGEF_PHaa 650–779UCSCSOS1/NGEF-like PH domain

SH3_1aa 799–842UCSCSH3 domain

Gene Aliases

HGNC Name

Rho guanine nucleotide exchange factor 26

HGNC Alias Symbols

DKFZP434D146; SGEF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015595.4

p.P147insFs

c.440dupC

Surrounding Variants

1 paper

NM_015595.4

p.R148fs

c.442_443fs

1 paper

NM_015595.4

p.A137insFs

c.409_410ins10

1 paper

NM_015595.4

p.A137fs

c.409_410fs

1 paper

NM_015595.4

p.A137_P138del1

c.410_412delCGC

1 paper

NM_015595.4

p.A137_P139del0

c.410_415del6

1 paper

NM_015595.4

p.A137_P138del2

c.409_413del6

1 paper

NM_015595.4

p.P155L

c.464C>T

1 paper

NM_015595.4

p.L135*

c.404T>A

1 paper

NM_015595.4

p.A132_P142del11

c.394_425del33

1 paper

NM_015595.4

p.S127S

c.381C>T

1 paper

NM_015595.4

p.P125R

c.374C>G

1 paper

NM_015595.4

p.P125S

c.373C>T