Varaico: Literature-Extracted Genetic Variants

ARHGEF26

88 papers

RefSeq Summary

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifical...

Pfam Domains

RhoGEFaa 443–621UCSCRhoGEF domain

SOS1_NGEF_PHaa 650–779UCSCSOS1/NGEF-like PH domain

SH3_1aa 799–842UCSCSH3 domain

Gene Aliases

HGNC Name

Rho guanine nucleotide exchange factor 26

HGNC Alias Symbols

DKFZP434D146; SGEF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_015595.4

p.F203S

c.608T>C

Surrounding Variants

1 paper

NM_015595.4

p.P204S

c.610C>T

1 paper

NM_015595.4

p.S211L

c.632C>T

1 paper

NM_015595.4

p.R193L

c.578G>T

1 paper

NM_015595.4

p.N225D

c.673A>G

1 paper

NM_015595.4

p.P231S

c.691C>T

1 paper

NM_015595.4

p.Q248*

c.742C>T

1 paper

NM_015595.4

p.P155L

c.464C>T

1 paper

NM_015595.4

p.R148fs

c.442_443fs

1 paper

NM_015595.4

p.I259_K260insAG

c.775_779ins6

1 paper

NM_015595.4

p.I259_K260insAGA

c.775_779ins9

1 paper

NM_015595.4

p.P147insFs

c.440dupC

1 paper

NM_015595.4

p.S262_K263insA

c.784_788ins3