Varaico: Literature-Extracted Genetic Variants

ARHGEF4

58 papers

RefSeq Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form ...

Pfam Domains

SH3_1aa 1386–1431UCSCSH3 domain

RhoGEFaa 1474–1652UCSCRhoGEF domain

SOS1_NGEF_PHaa 1680–1790UCSCSOS1/NGEF-like PH domain

Gene Aliases

HGNC Name

Rho guanine nucleotide exchange factor 4

HGNC Alias Symbols

STM6; KIAA1112; ASEF; ASEF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001367493.1

p.K358N

c.1074G>C

Surrounding Variants

2 papers

NM_001367493.1

p.E365A

c.1094A>C

1 paper

NM_001367493.1

p.S290L

c.869C>T

1 paper

NM_001367493.1

p.R434R

c.1302G>A

1 paper

NM_001367493.1

p.E272*

c.814G>T

2 papers

NM_001367493.1

p.L251P

c.752T>C

1 paper

NM_001367493.1

p.R249W

c.745A>T

1 paper

NM_001367493.1

p.Y221C

c.662A>G

1 paper

NM_001367493.1

p.S209F

c.626C>T

1 paper

NM_001367493.1

p.D204A

c.611A>C

1 paper

NM_001367493.1

p.R521K

c.1562G>A

1 paper

NM_001367493.1

p.G193S

c.577G>A

1 paper

NM_001367493.1

p.R187G

c.559A>G