Varaico: Literature-Extracted Genetic Variants

ARIH2

44 papers

RefSeq Summary

The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may ...

Pfam Domains

UBA_ARIH2_Naa 66–120UCSCE3 ubiquitin-protein ligase ARIH2, N-terminal UBA domain

zf-C3HC4aa 139–190UCSCZinc finger, C3HC4 type (RING finger)

IBRaa 208–270UCSCIBR domain, a half RING-finger domain

IBR_1aa 292–341UCSCIBR domain

Ariadneaa 363–482UCSCAriadne domain

Gene Aliases

HGNC Name

ariadne RBR E3 ubiquitin protein ligase 2

HGNC Alias Symbol

TRIAD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006321.4

p.E14K

c.40G>A

Surrounding Variants

1 paper

NM_006321.4

p.D11D

c.33C>T

1 paper

NM_006321.4

p.E29_D30del1

c.87_89delAGA

1 paper

NM_006321.4

p.E25K

c.73G>A

4 papers

NM_006321.4

p.E29D

c.87A>C

3 papers

NM_006321.4

p.E29D

c.87A>T

1 paper

NM_006321.4

p.E57E

c.171G>A