ATPase H+ transporting V1 subunit C2

VMA5

ATP6C2

ATPase, H+ transporting, lysosomal 42kD, V1 subunit C isoform 2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C isoform 2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

V-ATPase subunit C2

V-type proton ATPase subunit C 2

Vacuolar proton pump subunit C 2

V-ATPase subunit C 2

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

ATP6V1C2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols