Varaico: Literature-Extracted Genetic Variants

AXIN2

682 papers

RefSeq Summary

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil....

Pfam Domains

AXIN1_TNKS_BDaa 9–75UCSCAxin-1 tankyrase binding domain

RGSaa 81–199UCSCRegulator of G protein signaling domain

Axin_b-cat_bindaa 433–469UCSCAxin beta-catenin binding motif

DIXaa 763–839UCSCDIX domain

Gene Aliases

HGNC Name

axin 2

HGNC Alias Symbols

MGC126582; DKFZp781B0869

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

23 papers

NM_004655.4

p.G665insFs

c.1994_1995insG

NM_001363813.1

p.G600insFs

c.1994dupG

Surrounding Variants

15 papers

NM_004655.4

p.G665fs

c.1993_1994fs

20 papers

NM_004655.4

p.G665delFs

c.1994delC

1 paper

NM_004655.4

p.G665delins

c.1994_1995delinsCA

1 paper

NM_004655.4

p.G665A

c.1994G>C

10 papers

NM_004655.4

p.N666fs

c.1996_1997fs

9 papers

NM_004655.4

p.G665fs

c.1993_1994fs

1 paper

NM_004655.4

p.N666S

c.1997A>G

1 paper

NM_004655.4

p.G664G

c.1992G>A

3 papers

NM_004655.4

p.N666fs

c.1996_1997fs

1 paper

NM_004655.4

p.G664V

c.1991G>T

1 paper

NM_004655.4

p.S667fs

c.1999_2000fs

2 papers

NM_004655.4

p.S667insFs

c.1999dupA