Varaico: Literature-Extracted Genetic Variants

AXIN2

682 papers

RefSeq Summary

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil....

Pfam Domains

AXIN1_TNKS_BDaa 9–75UCSCAxin-1 tankyrase binding domain

RGSaa 81–199UCSCRegulator of G protein signaling domain

Axin_b-cat_bindaa 433–469UCSCAxin beta-catenin binding motif

DIXaa 763–839UCSCDIX domain

Gene Aliases

HGNC Name

axin 2

HGNC Alias Symbols

MGC126582; DKFZp781B0869

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004655.4

p.M1T

c.2T>C

Surrounding Variants

2 papers

NM_004655.4

p.M1R

c.2T>G

1 paper

NM_004655.4

p.M1K

c.2T>A

1 paper

NM_004655.4

p.M1fs

c.1_2fs

1 paper

NM_004655.4

p.M1_S2insFs

c.3_4insA

2 papers

NM_004655.4

p.M1V

c.1A>G

1 paper

NM_004655.4

p.S2G

c.4A>G

1 paper

NM_004655.4

p.M1_S2delFs

c.3_6del4

1 paper

NM_004655.4

p.A4P

c.10G>C

1 paper

NM_004655.4

p.L6L

c.16T>C

1 paper

NM_004655.4

p.V7L

c.19G>T

1 paper

NM_004655.4

p.S3_L6del4

c.7_17del12

1 paper

NM_004655.4

p.T8insFs

c.23dupC