Varaico: Literature-Extracted Genetic Variants

AXL

493 papers

RefSeq Summary

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobuli...

Pfam Domains

Ig_3aa 37–119UCSCImmunoglobulin domain

fn3aa 226–327UCSCFibronectin type III domain

fn3aa 335–424UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 536–803UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

AXL receptor tyrosine kinase

HGNC Alias Symbols

UFO; JTK11; Tyro7

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021913.5

p.E146K

c.436G>A

Surrounding Variants

1 paper

NM_021913.5

p.D147V

c.440A>T

1 paper

NM_021913.5

p.L142M

c.424C>A

5 papers

NM_021913.5

p.V150A

c.449T>C

1 paper

NM_021913.5

p.Y140C

c.419A>G

1 paper

NM_021913.5

p.N153S

c.458A>G

1 paper

NM_021913.5

p.T154P

c.460A>C

1 paper

NM_021913.5

p.C160Y

c.479G>A

1 paper

NM_021913.5

p.C160F

c.479G>T

1 paper

NM_021913.5

p.Q161H

c.483A>T

1 paper

NM_021913.5

p.P165T

c.493C>A

1 paper

NM_021913.5

p.P166S

c.496C>T

1 paper

NM_021913.5

p.E167fs

c.499_500fs