Varaico: Literature-Extracted Genetic Variants

Gene:BAG3
Variant:p.K449*

BAG3

535 papers

RefSeq Summary

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but di...

Pfam Domains

WWaa 22–52UCSCWW domain
BAGaa 425–497UCSCBAG domain

Gene Aliases

HGNC Name

BAG cochaperone 3

HGNC Previous Name

BCL2 associated athanogene 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_004281.4
p.K449*
c.1345A>T
Surrounding Variants
1 paper
NM_004281.4
p.K449T
c.1346A>C
1 paper
NM_004281.4
p.D448D
c.1344C>T
1 paper
NM_004281.4
p.K449_K450del2
c.1345_1349del6
1 paper
NM_004281.4
p.D448delFs
c.1344delC
1 paper
NM_004281.4
p.K450*
c.1348A>T
2 papers
NM_004281.4
p.D448N
c.1342G>A
1 paper
NM_004281.4
p.D448fs
c.1342_1343fs
6 papers
NM_004281.4
p.Y451*
c.1353C>A
5 papers
NM_004281.4
p.Y451*
c.1353C>G
1 paper
NM_004281.4
p.L452_M453del2
c.1354_1358del6
1 paper
NM_004281.4
p.L452L
c.1354C>T
1 paper
NM_004281.4
p.L452_M453del1
c.1355_1357delTGA
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