Varaico: Literature-Extracted Genetic Variants

Gene:BAG3
Variant:p.L458L

BAG3

535 papers

RefSeq Summary

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but di...

Pfam Domains

WWaa 22–52UCSCWW domain
BAGaa 425–497UCSCBAG domain

Gene Aliases

HGNC Name

BAG cochaperone 3

HGNC Previous Name

BCL2 associated athanogene 3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004281.4
p.L458L
c.1372T>C
Surrounding Variants
1 paper
NM_004281.4
p.T459A
c.1375A>G
1 paper
NM_004281.4
p.Y457H
c.1369T>C
34 papers
NM_004281.4
p.E455K
c.1363G>A
1 paper
NM_004281.4
p.I454M
c.1362C>G
1 paper
NM_004281.4
p.I454I
c.1362C>T
17 papers
NM_004281.4
p.L462P
c.1385T>C
2 papers
NM_004281.4
p.L452P
c.1355T>C
1 paper
NM_004281.4
p.L452L
c.1354C>T
1 paper
NM_004281.4
p.L452_M453del1
c.1355_1357delTGA
6 papers
NM_004281.4
p.Y451*
c.1353C>A
5 papers
NM_004281.4
p.Y451*
c.1353C>G
1 paper
NM_004281.4
p.L452_M453del2
c.1354_1358del6
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