Varaico: Literature-Extracted Genetic Variants

Gene:BCAR3
Variant:p.P818L

BCAR3

202 papers

RefSeq Summary

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resista...

Pfam Domains

SH2aa 154–234UCSCSH2 domain
RasGEFaa 551–730UCSCRasGEF domain

Gene Aliases

HGNC Name

BCAR3 adaptor protein, NSP family member

HGNC Alias Symbols

NSP2; SH2D3B; AND-34; MIG7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_003567.4
p.P818L
c.2453C>T
Surrounding Variants
1 paper
NM_003567.4
p.S812L
c.2435C>T
1 paper
NM_003567.4
p.S812*
c.2435C>A
2 papers
NM_003567.4
p.E802D
c.2406G>T
2 papers
NM_003567.4
p.E802D
c.2406G>C
1 paper
NM_003567.4
p.G789_T798delFs
c.2367_2394del28
1 paper
NM_003567.4
p.Q797R
c.2390A>G
1 paper
NM_003567.4
p.P770L
c.2309C>T
3 papers
NM_003567.4
p.I739V
c.2215A>G
2 papers
NM_003567.4
p.N733S
c.2198A>G
1 paper
NM_003567.4
p.E731G
c.2192A>G
1 paper
NM_003567.4
p.E731K
c.2191G>A
1 paper
NM_003567.4
p.M729V
c.2185A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."