Varaico: Literature-Extracted Genetic Variants

Gene:BCAR3
Variant:p.M729V

BCAR3

202 papers

RefSeq Summary

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resista...

Pfam Domains

SH2aa 154–234UCSCSH2 domain
RasGEFaa 551–730UCSCRasGEF domain

Gene Aliases

HGNC Name

BCAR3 adaptor protein, NSP family member

HGNC Alias Symbols

NSP2; SH2D3B; AND-34; MIG7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003567.4
p.M729V
c.2185A>G
Surrounding Variants
2 papers
NM_003567.4
p.D728N
c.2182G>A
1 paper
NM_003567.4
p.E731K
c.2191G>A
1 paper
NM_003567.4
p.E731G
c.2192A>G
2 papers
NM_003567.4
p.N733S
c.2198A>G
1 paper
NM_003567.4
p.F724S
c.2171T>C
1 paper
NM_003567.4
p.V722L
c.2164G>C
1 paper
NM_003567.4
p.Q720*
c.2158C>T
1 paper
NM_003567.4
p.R719C
c.2155C>T
3 papers
NM_003567.4
p.I739V
c.2215A>G
1 paper
NM_003567.4
p.E718A
c.2153A>C
1 paper
NM_003567.4
p.P712P
c.2136G>A
2 papers
NM_003567.4
p.T698I
c.2093C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."